Figure 1: Two reciprocal translocations of case MI2 with a karyotype of 46,XY,t(5;9)(p13.3;p22),t(7;21)(p13;q22.1). The upper panel shows the normal chromosomes 5, 7, 9, and 21, and the lower panel shows the respective derivative chromosomes. Bars in red, green, orange, and purple indicate chromosomal segments on chromosomes 5, 7, 9, and 21, respectively. Each dotted line indicates a breakpoint junction on each chromosome. A small white bar indicates a copy number loss of 15.4 kb involving the intron 3 of PTPRD in chromosome 9. Disruption of candidate genes associated with male infertility is shown above the chromosomes. PTPRD: protein tyrosine phosphatase receptor type D; chr: chromosome; der: derivative chromosome.