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  Indian J Med Microbiol
 

Figure 5: Schematic representation of the sperm renin angiotensin system, with the alterations (in bold) that occur in its axes in spermatozoa with DNA fragmentation. Due to the principal location of the enzymes and receptors altered in this principal axis of renin angiotensin system (RAS) (the tail of spermatozoa), it could be suggested that the spermatic motility is modified in DNA fragmented cells. ACE: angiotensin-converting enzyme; NEP: neutral endopeptidase; PEP: prolyl endopeptidase; MasR: angiotensin (A) 1–7 or Mas receptor; APN: aminopeptidase N; APA: aminopeptidase A; APB: aminopeptidase B; AT1R: A II receptor type 1; AT2R: A II receptor type 2; AT4R: A IV receptor; PRR: (pro)renin receptor.

Figure 5: Schematic representation of the sperm renin angiotensin system, with the alterations (in bold) that occur in its axes in spermatozoa with DNA fragmentation. Due to the principal location of the enzymes and receptors altered in this principal axis of renin angiotensin system (RAS) (the tail of spermatozoa), it could be suggested that the spermatic motility is modified in DNA fragmented cells. ACE: angiotensin-converting enzyme; NEP: neutral endopeptidase; PEP: prolyl endopeptidase; MasR: angiotensin (A) 1–7 or Mas receptor; APN: aminopeptidase N; APA: aminopeptidase A; APB: aminopeptidase B; AT1R: A II receptor type 1; AT2R: A II receptor type 2; AT4R: A IV receptor; PRR: (pro)renin receptor.