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Figure 1: Androgen inhibits miR-760 expression depending on the androgen receptor. (a) qPCR analysis of miR-760 in LNCaP and 22rv1 cells that were treated with vehicle or R1881. (b) qPCR analysis of miR-760 in DU145 and PC3 cells that were treated with vehicle or R1881. (c) qPCR analysis of miR-760 in AR knockdown LNCaP and 22rv1 cells that were treated with vehicle or R1881. (d) qPCR analysis of miR-760 in AR-overexpressing DU145 and PC3 cells that were treated with vehicle or R1881. *P < 0.05, **P < 0.01. NS: no significance; qPCR: quantitative polymerase chain reaction; AR: androgen receptor. |
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