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  Indian J Med Microbiol
 

Figure 1: The effect of high-fat diet with metformin treatment on testicular morphology. (a) Percentage of normal seminiferous tubules. (b) Percentage of tubules that displayed a degrading seminiferous epithelium. (c) Representative images of testicular morphology at different magnifications. Scale bars in the top row represent 500 μm, while scale bars in the bottom row represent 100 μm. Black arrows point to tubules containing vacuoles and yellow arrows represent tubules with a degrading seminiferous epithelium. Data are expressed as mean ± s.e.m. Data are representative of n = 8 control diet, n = 7 high-fat diet and n = 7 high-fat diet + metformin males. a and b letters denote significance at P < 0.05. Figures bearing the same superscript letter are not significantly different. CD: control diet; HFD: high-fat diet; s.e.m.: standard error of the mean.

Figure 1: The effect of high-fat diet with metformin treatment on testicular morphology. (<b>a</b>) Percentage of normal seminiferous tubules. (<b>b</b>) Percentage of tubules that displayed a degrading seminiferous epithelium. (<b>c</b>) Representative images of testicular morphology at different magnifications. Scale bars in the top row represent 500 μm, while scale bars in the bottom row represent 100 μm. Black arrows point to tubules containing vacuoles and yellow arrows represent tubules with a degrading seminiferous epithelium. Data are expressed as mean ± s.e.m. Data are representative of <Italic>n</Italic> = 8 control diet, <i>n</i> = 7 high-fat diet and <i>n</i> = 7 high-fat diet + metformin males. a and b letters denote significance at  <i>P</i> < 0.05. Figures bearing the same superscript letter are not significantly different. CD: control diet; HFD: high-fat diet; s.e.m.: standard error of the mean.