Figure 3: Anterior tumor in 38 ml prostate. Axial view of 2.3 cm lesion on T2-weighted imaging ( a ), dynamic contrast-enhanced imaging ( b ), diffusion-weighted imaging ( c ), transrectal ultrasound with segmented prostate and regions of interest and biopsy trajectories ( d ), reconstructed 3D view of prostate showing regions of interest and biopsy tracks ( e ), example of targeted biopsy report-incorporating key aspects of urology, radiology and pathology components-in use at UCLA ( f ). Smaller targets were negative for cancer. Anterior tumors may be missed by conventional biopsy; in this case, two prior 'saturation' biopsies had failed to detect the tumor, a Gleason 7 cancer. UCLA: University of California, Los Angeles.