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  Indian J Med Microbiol
 

Figure 2: The therapeutic effect of finasteride on SRD5A2-negative BPH-1 cells. (a) In BPH-1 cells, positivity for DNMT1 mRNA and SRD5A1 mRNA was observed, while SRD5A2 mRNA was not expressed. “M” represents the molecular weight standard. (b) Finasteride promoted the viability of BPH-1 cells, rather than inducing cell death. (c) Finasteride repressed BPH-1 cell apoptosis. (d) Finasteride inhibited BPH-1 cell necrosis. DNMT1: DNA methyltransferase 1; SRD5A2: 5-α reductase type 2; SRD5A1: 5-α reductase type 1; GAPDH: glyceraldehyde-3-phosphate dehydrogenase.

Figure 2: The therapeutic effect of finasteride on SRD5A2-negative BPH-1 cells. (<b>a</b>) In BPH-1 cells, positivity for <i>DNMT1</i> mRNA and <i>SRD5A1</i> mRNA was observed, while <i>SRD5A2</i> mRNA was not expressed. “M” represents the molecular weight standard. (<b>b</b>) Finasteride promoted the viability of BPH-1 cells, rather than inducing cell death. (<b>c</b>) Finasteride repressed BPH-1 cell apoptosis. (<b>d</b>) Finasteride inhibited BPH-1 cell necrosis. <i>DNMT1</i>: DNA methyltransferase 1; <i>SRD5A2</i>: 5-α reductase type 2; <i>SRD5A1</i>: 5-α reductase type 1; <i>GAPDH</i>: glyceraldehyde-3-phosphate dehydrogenase.