Figure 2: The therapeutic effect of finasteride on SRD5A2-negative BPH-1 cells. (a) In BPH-1 cells, positivity for DNMT1 mRNA and SRD5A1 mRNA was observed, while SRD5A2 mRNA was not expressed. “M” represents the molecular weight standard. (b) Finasteride promoted the viability of BPH-1 cells, rather than inducing cell death. (c) Finasteride repressed BPH-1 cell apoptosis. (d) Finasteride inhibited BPH-1 cell necrosis. DNMT1: DNA methyltransferase 1; SRD5A2: 5-α reductase type 2; SRD5A1: 5-α reductase type 1; GAPDH: glyceraldehyde-3-phosphate dehydrogenase.