Asian Journal of Andrology

ORIGINAL ARTICLE
Year
: 2014  |  Volume : 16  |  Issue : 6  |  Page : 884--891

The effectiveness and safety of acupuncture for poor semen quality in infertile males: a systematic review and meta-analysis


Ui Min Jerng1, Jun-Young Jo2, Seunghoon Lee3, Jin-Moo Lee4, Ohmin Kwon5 
1 Class of Oncology, Department of Clinical Korean Medicine, Kyung Hee University Graduate School, Seoul, Korea
2 Class of Gynecology, Department of Clinical Korean Medicine, Kyung Hee University Graduate School; Conmaul Hospital, Seoul, Korea
3 Class of Acupuncture and Moxibustion, Department of Clinical Korean Medicine, Kyung Hee University Graduate School, Seoul, Korea
4 Class of Gynecology, Department of Clinical Korean Medicine, Kyung Hee University Graduate School, Seoul, Korea
5 Medical History and Literature Group, Korea Institute of Oriental Medicine, Daejeon, Korea

Correspondence Address:
Ohmin Kwon
Medical History and Literature Group, Korea Institute of Oriental Medicine, Daejeon
Korea

The aim of this review is to evaluate the effectiveness and safety of acupuncture for poor semen quality in infertile men. We searched for relevant trials registered up to May 2013 in 14 databases. We selected randomized controlled trials (RCTs) that compared acupuncture, with or without additional treatment, against placebo, sham, no treatment, or the same additional treatment. Two reviewers independently performed the study selection, data extraction, risk of bias and reporting quality appraisal. Risk of bias and reporting quality were appraised by the Cochrane risk of bias tool, the consolidated standards of reporting trials and Standards for Reporting Interventions in Clinical Trials of Acupuncture. The outcomes were sperm motility, sperm concentration, pregnancy rate, and adverse events. Pregnancy was defined as a positive pregnancy test. Four RCTs met the eligibility criteria. Acupuncture increased the percentage of sperm with rapid progression (mean difference - 6.35, 95% confidence interval (CI): 4.38-8.32, P< 0.00001) and sperm concentration (mean difference - 6.42, 95% CI: 4.91-7.92, P< 0.00001), but these two outcomes were substantially heterogeneous among the studies (I 2 = 72% and 58%, respectively). No differences in pregnancy rate were found between acupuncture and control groups (odds ratio 1.60, 95% CI: 0.70-3.69, P= 0.27, I 2 = 0%). No participants experienced adverse events. The current evidence showing that acupuncture might improve poor semen quality is insufficient because of the small number of studies, inadequacy of procedures and/or insufficient information for semen analysis, high levels of heterogeneity, high risk of bias, and poor quality of reporting. Further large, well-designed RCTs are required.


How to cite this article:
Jerng UM, Jo JY, Lee S, Lee JM, Kwon O. The effectiveness and safety of acupuncture for poor semen quality in infertile males: a systematic review and meta-analysis.Asian J Androl 2014;16:884-891


How to cite this URL:
Jerng UM, Jo JY, Lee S, Lee JM, Kwon O. The effectiveness and safety of acupuncture for poor semen quality in infertile males: a systematic review and meta-analysis. Asian J Androl [serial online] 2014 [cited 2021 Sep 28 ];16:884-891
Available from: https://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=6;spage=884;epage=891;aulast=Jerng;type=0