Asian Journal of Andrology

INVITED RESEARCH HIGHLIGHT
Year
: 2014  |  Volume : 16  |  Issue : 4  |  Page : 561--564

Androgen receptor functions in prostate cancer development and progression


Steven P Balk 
 Division of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA

Correspondence Address:
Steven P Balk
Division of Hematology-Oncology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
USA

The androgen receptor (AR) is critical for the normal development of prostate and for its differentiated functions. The consistent expression of AR in prostate cancer (PCa), and its continued activity in PCa that relapse after androgen deprivation therapy (castration-resistant prostate cancer (CRPC)), indicate that at least a subset of these genes are also critical for PCa development and progression. This review addressed AR regulated genes that may be critical for PCa, and how AR may acquire new functions during PCa development and progression.


How to cite this article:
Balk SP. Androgen receptor functions in prostate cancer development and progression.Asian J Androl 2014;16:561-564


How to cite this URL:
Balk SP. Androgen receptor functions in prostate cancer development and progression. Asian J Androl [serial online] 2014 [cited 2021 Jan 25 ];16:561-564
Available from: https://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=561;epage=564;aulast=Balk;type=0