The molecular control of meiotic double-strand break (DSB) formation and its significance in human infertility

Yang Li¹, Yu-Fan Wu¹, Han-Wei Jiang¹, Ranjha Khan¹, Qi-Qi Han¹, Furhan Iqbal², Xiao-Hua Jiang¹, Qing-Hua Shi^1
1 Division of Reproduction and Genetics, First Affiliated Hospital of USTC, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, CAS Center for Excellence in Molecular Cell Science, Collaborative Innovation Center of Genetics and Development, University of Science and Technology of China, Hefei 230027, China
² Institute of Pure and Applied Biology, Bahauddin Zakariya University, Multan 60000, Pakistan

Correspondence Address:
Qing-Hua Shi,
Division of Reproduction and Genetics, First Affiliated Hospital of USTC, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, CAS Center for Excellence in Molecular Cell Science, Collaborative Innovation Center of Genetics and Development, University of Science and Technology of China, Hefei 230027
China
Xiao-Hua Jiang,
Division of Reproduction and Genetics, First Affiliated Hospital of USTC, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, CAS Center for Excellence in Molecular Cell Science, Collaborative Innovation Center of Genetics and Development, University of Science and Technology of China, Hefei 230027
China

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aja.aja_5_21

PMID: 33586697