INVITED REVIEW
Year : 2015  |  Volume : 17  |  Issue : 3  |  Page : 421-426

Germline-competent stem cell in avian species and its application


1 Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul-151 921, Korea
2 Graduate School of International Agricultural Technology and Institute of Green Bio Science and Technology, Seoul National University, Pyeongchang-gun, Gangwon-do 232-916, Korea

Correspondence Address:
Jae Yong Han
Department of Agricultural Biotechnology, College of Agriculture and Life Sciences, and Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul-151 921
Korea
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1008-682X.148073

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Germ cells are the only cell type in the body that can transfer genetic information to the next generation. Germline-competent stem cells can self-renew and contribute to the germ cell lineage giving rise to pluripotent stem cells under specific conditions. Hence far, studies on germline-competent stem cells have contributed to the generation of avian model systems and the conservation of avian genetic resources. In this review, we focus on previous studies on germline-competent stem cells from avian species, mainly chicken germline-competent stem cells, which have been well established and characterized. We discuss different sources of germline-competent stem cells and recent advances for the future applications in birds.


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