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  Indian J Med Microbiol
 

Figure 3: Interaction between the DEPs and their association with transcription regulators in bilateral varicocele in comparison to fertile men. IL-6: interleukin 6; Shc: Shc transforming protein; NF-κB: nuclear factor-kappa B, PIGR: polymeric immunoglobulin receptor; B2M: beta-2 microglobulin; GLO1: glyoxalase I; FN1: fibronectin1; IRF1: interferon regulatory factor 1; PKC: protein kinase C; ANXA5: annexin5; ERK1/2: extracellular signal-regulated kinases; AP-1: activator protein 1; PRDX2: peroxiredoxin 2; PRDX1: peroxiredoxin 1; NRF2: nuclear factor erythroid 2 (NFE2)-related factor 2; AKR1B1: aldose reductase; PIP: prolactin-induced protein; TR: transcription regulation; +P: phosphorylation; B: binding; AP-1: activating protein-1.

Figure 3: Interaction between the DEPs and their association with transcription regulators in bilateral varicocele in comparison to fertile men. IL-6: interleukin 6; Shc: Shc transforming protein; NF-κB: nuclear factor-kappa B, PIGR: polymeric immunoglobulin receptor; B2M: beta-2 microglobulin; GLO1: glyoxalase I; FN1: fibronectin1; IRF1: interferon regulatory factor 1; PKC: protein kinase C; ANXA5: annexin5; ERK1/2: extracellular signal-regulated kinases; AP-1: activator protein 1; PRDX2: peroxiredoxin 2; PRDX1: peroxiredoxin 1; NRF2: nuclear factor erythroid 2 (NFE2)-related factor 2; AKR1B1: aldose reductase; PIP: prolactin-induced protein; TR: transcription regulation; +P: phosphorylation; B: binding; AP-1: activating protein-1.