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  Indian J Med Microbiol
 

Figure 2: DNA/histone-modifying enzymes are targeted for the development of epigenetic drugs. HAT: histone acetyltransferase; HDAC: histone deacetylase; HMT: histone methyltransferase; HDM: histone demethylase; DNMT: DNA methyltransferase; BET: the bromodomain and extra-terminal domain. Green triangle: acetyl functional group; pink diamond: methyl modification; orange pentagon: ADP-ribose moiety; FCDR: 5-fluorodeoxycytidine; SGI-110: guadecitabine; RG108: N-phthalyl-l-tryptophan; EGCG: epigallocatechin-3-gallate; MG98: DNA methyltransferase-1 by antisense.

Figure 2: DNA/histone-modifying enzymes are targeted for the development of epigenetic drugs. HAT: histone acetyltransferase; HDAC: histone deacetylase; HMT: histone methyltransferase; HDM: histone demethylase; DNMT: DNA methyltransferase; BET: the bromodomain and extra-terminal domain. Green triangle: acetyl functional group; pink diamond: methyl modification; orange pentagon: ADP-ribose moiety; FCDR: 5-fluorodeoxycytidine; SGI-110: guadecitabine; RG108: N-phthalyl-l-tryptophan; EGCG: epigallocatechin-3-gallate; MG98: DNA methyltransferase-1 by antisense.