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  Indian J Med Microbiol
 

Figure 2: Schematic representation of BMI1 participation in the initiation, progression, and relapse of prostate cancer. ADT: androgen deprivation therapy; AR: androgen receptor; BMI1: B-cell-specific MMLV insertion region 1; CRPC: castration-resistant prostate cancer; PRC1: polycomb repression complex 1; PTEN: phosphatase and tensin homolog; hTERT: human telomerase reverse transcriptase; TOP2A: topoisomerase 2-alpha.

Figure 2: Schematic representation of BMI1 participation in the initiation, progression, and relapse of prostate cancer. ADT: androgen deprivation therapy; AR: androgen receptor; BMI1: B-cell-specific MMLV insertion region 1; CRPC: castration-resistant prostate cancer; PRC1: polycomb repression complex 1; PTEN: phosphatase and tensin homolog; hTERT: human telomerase reverse transcriptase; TOP2A: topoisomerase 2-alpha.