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  Indian J Med Microbiol
 

Figure 3: Cut-off value for the screening of Klinefelter syndrome. (a) RSD range for 46,XY samples. (b) Resolution of the high-resolution melting assay for detecting 46,XY/47,XYY mosaicism. Statistical analysis: the line within the box denotes the median, the square within the box denotes the mean, the horizontal borders of each box denote the 25th and 75th percentiles, the whiskers denote the 5th and 95th percentiles, and the stars denote the maximum and minimum. (c) Analytical sensitivity and specificity for 46,XY/47,XYY mosaicism detection with different cut-off values. RSD: relative signal difference.

Figure 3: Cut-off value for the screening of Klinefelter syndrome. (<b>a</b>) RSD range for 46,XY samples. (<b>b</b>) Resolution of the high-resolution melting assay for detecting 46,XY/47,XYY mosaicism. Statistical analysis: the line within the box denotes the median, the square within the box denotes the mean, the horizontal borders of each box denote the 25<sup>th</sup> and 75<sup>th</sup> percentiles, the whiskers denote the 5<sup>th</sup> and 95<sup>th</sup> percentiles, and the stars denote the maximum and minimum. (<b>c</b>) Analytical sensitivity and specificity for 46,XY/47,XYY mosaicism detection with different cut-off values. RSD: relative signal difference.