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  Indian J Med Microbiol
 

Figure 3: Calpain expression and activity. (a) The expressions of calpain-1, calpain-2, and the 145 kDa stable breakdown products of spectrin α-II were detected with Western blot. (b) Relative density of calpain-1, calpain-2, and stable breakdown products compared with β-actin. Data are shown as the fold changes over the control group. n = 4 for each group. (c) Calpain activity measured using a fluorescence substrate N-succinyl-LLVY-AMC. Data are shown as the fold changes over the control group. n = 3 for each group. Statistical analyses were conducted using one-way analysis of variance followed by the Tukey test. *P < 0.05, compared with control group. #P < 0.05, compared with DM group. DM: diabetes mellitus.

Figure 3: Calpain expression and activity. (<b>a</b>) The expressions of calpain-1, calpain-2, and the 145 kDa stable breakdown products of spectrin α-II were detected with Western blot. (<b>b</b>) Relative density of calpain-1, calpain-2, and stable breakdown products compared with β-actin. Data are shown as the fold changes over the control group. <i>n</i> = 4 for each group. (<b>c</b>) Calpain activity measured using a fluorescence substrate N-succinyl-LLVY-AMC. Data are shown as the fold changes over the control group. <i>n</i> = 3 for each group. Statistical analyses were conducted using one-way analysis of variance followed by the Tukey test. <sup>*</sup><i>P</i> < 0.05, compared with control group. <sup>#</sup><i>P</i> < 0.05, compared with DM group. DM: diabetes mellitus.