Close
  Indian J Med Microbiol
 

Figure 2: Potential detrimental metabolic actions of testosterone deficiency. In testosterone deficiency, excess deposition of fat resulting from poor lipid and glucose control and inadequate storage capacity in subcutaneous adipose depots may lead to “overspill” into visceral fat. Concurrently, testosterone deficiency and elevated circulating glucose and lipid cause further metabolic dysregulation in visceral adipose tissue, with ensuing metabolic consequences in liver and muscle, resulting in lipid accumulation. This ectopic lipid accumulation has pathological consequences when it is ultimately deposited in tissues such as the liver (hepatic steatosis) and the arterial wall (atherosclerosis).

Figure 2: Potential detrimental metabolic actions of testosterone deficiency. In testosterone deficiency, excess deposition of fat resulting from poor lipid and glucose control and inadequate storage capacity in subcutaneous adipose depots may lead to “overspill” into visceral fat. Concurrently, testosterone deficiency and elevated circulating glucose and lipid cause further metabolic dysregulation in visceral adipose tissue, with ensuing metabolic consequences in liver and muscle, resulting in lipid accumulation. This ectopic lipid accumulation has pathological consequences when it is ultimately deposited in tissues such as the liver (hepatic steatosis) and the arterial wall (atherosclerosis).