Figure 6: Immunohistochemistry for ERα and p63 proteins. (a-d) The stromal expression of ERα for all experimental groups. Observe the expression of ERα in the epithelium of TG and TG + T prostates (c and d), which suggests a more proliferative status between these experimental groups. e-h demonstrate the immunolocalization of p63 protein in the basal cell population in the prostate epithelium. We observed that the regularity of this cellular layer is lost in some injured areas of the prostate in the TG and TG + T groups (g and h), suggesting a changed pattern of p63 immunolocalization. Observe the absence of basal cells in some regions of the adenomatous hyperplasia (h). ep: epithelium; l: lumen; s: stroma; small arrows: ERα-positive cells; arrows: p63-positive cells. (a and e) C, (b and f) C + T, (c and g) TG and (d, h, i) TG + T. Scale bar: 20 μm in a-h .