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  Indian J Med Microbiol
 

Figure 3: siRNA-induced down-regulation of TIMELESS in PC3M cells reduces cell migration. ( a ) Treatment of PC3M cells with siTIMELESS leads to a marked reduction in TIMELESS protein levels, ( b ) but have no effect on cell proliferation. ( c ) A monolayer of PC3M cells was scratched to examine the rate of cell migration into the wounded area. The bar graph represents the percentage of cell-recovered wound areas after 24 h of incubation (*P < 0.01). Representative images of the wound captured at different time points are shown (at right). Results are representative of three individual experiments (mean ± S.D.). S.D., standard deviation.

Figure 3: siRNA-induced down-regulation of <i>TIMELESS</i> in PC3M cells reduces cell migration. ( <b>a</b> ) Treatment of PC3M cells with siTIMELESS leads to a marked reduction in TIMELESS protein levels, ( <b>b</b> ) but have no effect on cell proliferation. ( <b>c</b> ) A monolayer of PC3M cells was scratched to examine the rate of cell migration into the wounded area. The bar graph represents the percentage of cell-recovered wound areas after 24 h of incubation (*<i>P</i> < 0.01). Representative images of the wound captured at different time points are shown (at right). Results are representative of three individual experiments (mean ± S.D.). S.D., standard deviation.