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  Indian J Med Microbiol
 

Figure 2: Mtor KO mice progressively lose their germ cells and fertility with age. (a) Representative images of testes from control and Mtor KO mice aged from 1 to 32 weeks old. Scale bar = 3mm. (b) Quantification of testis weight to body weight ratios of control and Mtor KO mice at different ages. (c) Representative images of H and E-stained testicular sections of control and Mtor KO mice aged from 8 weeks to 32 weeks old. Scale bars = 50 μm. (d) Representative images of H and E-stained cauda epididymal sections of control and Mtor KO mice at different ages. Scale bars = 100 μm. (e) Quantification of spermatozoa collected from the cauda epididymidis of control and Mtor KO mice at different ages. (f) Statistical analysis of the fertility of control and Mtor KO male mice at distinct age intervals. H and E: hematoxylin and eosin.*P < 0.05;**P < 0.01;***P < 0.001;****P < 0.0001.

Figure 2: <i>Mtor</i> KO mice progressively lose their germ cells and fertility with age. (a) Representative images of testes from control and <i>Mtor</i> KO mice aged from 1 to 32 weeks old. Scale bar = 3mm. (b) Quantification of testis weight to body weight ratios of control and <i>Mtor</i> KO mice at different ages. (c) Representative images of H and E-stained testicular sections of control and <i>Mtor</i> KO mice aged from 8 weeks to 32 weeks old. Scale bars = 50 μm. (d) Representative images of H and E-stained cauda epididymal sections of control and <i>Mtor</i> KO mice at different ages. Scale bars = 100 μm. (e) Quantification of spermatozoa collected from the cauda epididymidis of control and <i>Mtor</i> KO mice at different ages. (f) Statistical analysis of the fertility of control and <i>Mtor</i> KO male mice at distinct age intervals. H and E: hematoxylin and eosin.<sup>*</sup><i>P</i> < 0.05;<sup>**</sup><i>P</i> < 0.01;<sup>***</sup><i>P</i> < 0.001;<sup>****</sup><i>P</i> < 0.0001.