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Prostate cancer risk prediction models in Eastern Asian populations: current status, racial difference, and future directions


 Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433, China

Correspondence Address:
Xu Gao,
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433
China
Ying-Hao Sun,
Department of Urology, Changhai Hospital, Second Military Medical University, Shanghai 200433
China
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/aja.aja_55_19

Prostate cancer (PCa) risk calculators (RCs) with prostate-specific antigen (PSA) and other risk factors can greatly improve the accurate prediction of potential risk of PCa compared to PSA. The European Randomized Study of Screening for PCa Risk Calculator (ERSPC-RC) and the Prostate Cancer Prevention Trial Risk Calculator (PCPT-RC) are developed on the Western population. However, the Western RCs showed limited diagnostic efficacy in the Eastern Asian population, mainly due to racial differences between the two populations. We aimed to review the application of Western RCs and Eastern Asian RCs in Eastern Asian cohorts and to identify the characteristics and efficacy of these RCs.


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    -  He BM
    -  Chen R
    -  Sun TQ
    -  Yang Y
    -  Zhang CL
    -  Ren SC
    -  Gao X
    -  Sun YH
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