ORIGINAL ARTICLE
Year : 2019  |  Volume : 21  |  Issue : 4  |  Page : 408-412

Effects of percutaneous varicocele repair on testicular volume: results from a 12-month follow-up


1 Department of Experimental Medicine, Sapienza University of Rome, Rome 00161, Italy
2 Department of Public Health and Infectious Diseases, Sapienza University of Rome, Rome 00161, Italy
3 Unit of Endocrinology, Regina Elena National Cancer Institute, Rome 00144, Italy
4 Vascular and Interventional Radiology Unit, Department of Radiological, Oncological and Anatomo-Pathological Sciences, Sapienza - University of Rome, Rome 00161, Italy

Correspondence Address:
Daniele Gianfrilli
Department of Experimental Medicine, Sapienza University of Rome, Rome 00161
Italy
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/aja.aja_102_18

Rights and Permissions

Varicocele is a common finding in men. Varicocele correction has been advocated for young patients with testicular hypotrophy, but there is a lack of morphofunctional follow-up data. We assessed whether percutaneous treatment of left varicocele is associated with testicular “catch-up growth” in the following 12 months by retrospectively reviewing data from an electronic database of 10 656 patients followed up in our clinic between 2006 and 2016. We selected all young adults (<35 years) with left varicocele who underwent percutaneous treatment, had a minimum of 12 months' ultrasound imaging follow-up, and had no other conditions affecting testicular volume. One hundred and fourteen men (mean±standard deviation [s.d.] of age: 22.8 ± 5.4 years) met the inclusion and exclusion criteria. Left testicular hypotrophy (LTH), defined as a ≥20% difference between left and right testicular volume at baseline, was observed in 26 (22.8%) men. Participants with LTH (mean±s.d.: 14.5 ± 2.7 ml) had lower baseline testicular volume compared to those without LTH (mean±s.d.: 15.7 ± 3.8 ml; P = 0.032). Repeated measures mixed models showed a significant interaction between LTH and time posttreatment when correcting for baseline left testicular volume (β = 0.114, 95% confidence interval [CI]: 0.018–0.210, P = 0.020), resulting in a catch-up growth of up to 1.37 ml per year (95% CI: 0.221–2.516). Age at intervention was also associated with reduced testicular volume (−0.072 ml per year, 95% CI: −0.135–−0.009; P = 0.024). Percutaneous treatment of left varicocele in young adults with LTH can result in catch-up growth over 1 year of follow-up. The reproductive and psychological implications of these findings need to be confirmed in longer and larger prospective studies.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed677    
    Printed78    
    Emailed0    
    PDF Downloaded105    
    Comments [Add]    
    Cited by others 1    

Recommend this journal