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INVITED COMMENTARY
Year : 2014  |  Volume : 16  |  Issue : 4  |  Page : 640

Commentary on 'Decline of semen quality during IVF is not associated with subjective male stress'


Department of Dermatology, Andrology Unit, University of Bonn, Bonn, Germany

Date of Web Publication28-Mar-2014

Correspondence Address:
Gerhard Haidl
Department of Dermatology, Andrology Unit, University of Bonn, Bonn
Germany
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1008-682X.126376

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How to cite this article:
Haidl G. Commentary on 'Decline of semen quality during IVF is not associated with subjective male stress'. Asian J Androl 2014;16:640

How to cite this URL:
Haidl G. Commentary on 'Decline of semen quality during IVF is not associated with subjective male stress'. Asian J Androl [serial online] 2014 [cited 2019 Nov 15];16:640. Available from: http://www.ajandrology.com/text.asp?2014/16/4/640/126376 - DOI: 10.4103/1008-682X.126376

Amongst the reasons for male infertility the factor 'stress' is frequently cited, however, without providing more detailed explanations. In the article 'Decline of semen quality during IVF is not associated with subjective male stress' published on Asian Journal of Andrology, Nouri et al. [1] describe a decline in progressive sperm motility in a retrospective cohort of 155 male in vitro fertilization (IVF) patients during a time period of 4-6 weeks prior to the first IVF cycle and the time of oocyte retrieval. In a subsequent prospective cohort study on men undergoing their first IVF semen quality and subjective male chronic stress were investigated at the same time intervals. Subjective stress was assessed by the Fertility Problem Inventory questionnaire. In the prospective study, there was also a decline in progressive motility, whereas, sperm density increased. The comparison of sperm density and progressive motility revealed no differences between men with and without stress. However, in couples where the male partner suffered from chronic stress there was a higher rate of poor responders, miscarriages and a lower live birth rate.

The conclusion that subjective stress is not associated with a decline in semen quality observed during IVF is based on assessment of the basic semen parameters which allows only a rough estimation of semen quality. It may well have been the case that functional parameters like DNA integrity have been disturbed by the stress exposure as it was reported by Vellani et al.; [2] moreover, this phenomenon could explain the poor response and miscarriages in the stress group, but, of course, the adverse pregnancy outcome may have different reasons, for example increased feeling of stress on the female side.

On the other hand, the question remaining is why sperm motility declines in IVF patients regardless of the influence of subjective stress. In several reports using other diagnostic tools stress factors have been made responsible for reduced semen quality. [2] Perhaps the use of the Fertility Problem Inventory questionnaire may have failed to detect more subtle, unconscious aspects of stress.

The involvement of psychological factors in male infertility has been investigated for many years and a negative influence of psychological stress on spermatogenesis has been described. [3] The decline in sperm motility-the mainly affected parameter-could be better explained by a disturbance of epididymal function. Epididymal sperm maturation takes about 10 days. Therefore, in the case of IVF patients, acute stress may play a major role rather than chronic stress influence.

The epididymis is known as a stress-sensitive organ-epididymitis sympathica or erotica, [4] reacting directly on acute events, not least on stress prior to semen collection on the day of oocyte retrieval. A disturbed DNA-integrity can, among others, be referred to epididymal dysfunction as well.

However, both acute and chronic stress exposure warrants further investigation, because couples with an unfulfilled wish for a child face a continuing confrontation with frustrating thoughts and feelings which makes coping very difficult and may finally lead to problems like alexithymia, i.e., difficulty in communicating emotions and somatic complaints as well. [5]

Therefore, the article to be commented is highly recommended to readers because psychological aspects of male infertility deserve more consideration as it is usually the case.

 
  References Top

1.Nouri K, Litschauer B, Sator M, Tiringer D, Ott J, et al. Decline of semen quality during IVF is not associated with subjective male stress. Asian J Androl 2014; 16. doi: 10.4103/1008-682X.125404. [Epub ahead of print].  Back to cited text no. 1
    
2.Vellani E, Colasante A, Mamazza L, Minasi MG, Greco E, et al. Association of state and trait anxiety to semen quality of in vitro fertilization patients: a controlled study. Fertil Steril 2013; 99: 1565-72.  Back to cited text no. 2
    
3.Pook M, Krause W, Röhrle B. Coping with infertility: distress and changes in sperm quality. Hum Reprod 1999; 14: 1487−92.  Back to cited text no. 3
    
4.Chalett JM, Nerenberg LT. "Blue balls": a diagnostic consideration in testiculoscrotal pain in young adults: A case report and discussion. Pediatrics 2002; 106: 843.  Back to cited text no. 4
    
5.Conrad C, Schilling G, Langenbuch M, Haidl G, Liedtke R. Alexithymia in male infertility. Hum Reprod 2001; 16: 587-92.  Back to cited text no. 5
    




 

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