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Tumor-associated immune cells in prostate cancer

Prostate cancer is the most common malignancy in the reproductive system of older males. Although emerging approaches have been developed for the treatment of prostate cancer, most of prostate cancer patients still unavoidably progress to the therapeutic resistance stage. Recent studies have shown that tumor-associated immune cells play major roles in the initiation, progression, and metastasis of prostate cancer. Various phenotypes of tumor-associated immune cells have tumor-promoting or antitumor functions mediated by interacting with tumor cells. Even tumor-associated immune cells derived from the same origin can play various roles in different stages of prostate cancer. Here, we review the current knowledge of tumor associated immune cells in the development of prostate cancer. Please refer to pages 433–437.

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